Friday, March 22 (Round of 64)
- (8) Florida Atlantic vs. (9) Northwestern | 12:15 p.m. | CBS
- (3) Baylor vs. (14) Colgate | 12:40 p.m. | truTV
- (5) San Diego State vs. (12) UAB | 1:45 p.m. | TNT
- (2) Marquette vs. (15) Western Kentucky | 2 p.m. | TBS
- (1) UConn vs. (16) Stetson | 2:45 p.m. | CBS
- (6) Clemson vs. (11) New Mexico | 3:10 p.m. | truTV
- (4) Auburn vs. (13) Yale | 4:15 p.m. | TNT
- (7) Florida vs. (10) Colorado | 4:30 p.m. | TBS
- (8) Nebraska vs. (9) Texas A&M | 6:50 p.m. | TNT
- (4) Duke vs. (13) Vermont | 7:10 p.m. | CBS
- (1) Purdue vs. (16) Grambling | 7:25 p.m. | TBS
- (4) Alabama vs. (13) College of Charleston | 7:35 pm. | truTV
- (1) Houston vs. (16) Longwood | 9:20 p.m. | TNT
- (5) Wisconsin vs. (12) James Madison | 9:40 p.m. | CBS
- (8) Utah State vs. (9) TCU | 9:55 p.m. | TBS
- (5) Saint Mary's vs. (12) Grand Canyon | 10:05 p.m. | truTV
